While the strong materials and thought out design makes it extremely hard for predators to get to your pets, no hutch is 100% predator proof. Check the hutch and run regularly to make sure all features are working as intended, including latches, doors and run clips.
If you live in an area with lots of predators, including wild cats, bears, coyotes, possums, as well as smaller animals like minks weasels, and snakes you might want to consider adding additional protection to the run. If you've seen raccoons or other particularly dexterous animals around your yard, it's also a good idea to find a way to secure doors and latches with extra locks to stop them getting to your pets.